WebFeb 20, 2024 · Introduction to Peptidyl-Prolyl cis/trans Isomerase (PPIase) Series About 30 years after the discovery of peptidyl-prolyl cis/trans isomerases (PPIases), … WebPin 1, or peptidyl-prolyl cis/trans isomerase (PPIase), isomerizes only phospho-Serine/Threonine-Proline motifs. The enzyme binds to a subset of proteins and thus plays a role as a post phosphorylation control in regulating protein function. Studies have shown that the deregulation of Pin1 may play a pivotal role in various diseases.
23988 - Gene ResultPin1 peptidyl-prolyl cis/trans isomerase, NIMA ...
WebThe peptidyl-prolyl cis/trans isomerase Pin1 is a crucial regulator that is implicated in a wide variety of physiological and pathological activities. The deregulation of Pin1 expression and/or activity is associated with the development of cancer and neurodegeneration, including AD. Interestingly, Pin1 regulates the conformational change of ... WebPeptidyl-prolyl cis-trans isomerase B is an enzyme that is encoded by the PPIB gene. [5] As a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, this protein catalyzes the cis-trans isomerization of proline imidic peptide bonds, which allows it to regulate protein folding of type I collagen. sivesind brothers enterprises llc
FKBP-type peptidyl-prolyl cis-trans isomerase from thermophilic ...
Peptidylprolyl isomerase A (PPIA), also known as cyclophilin A (CypA) or rotamase A is an enzyme that in humans is encoded by the PPIA gene on chromosome 7. As a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, this protein catalyzes the cis-trans isomerization of proline imidic peptide bonds, which allows it to regulate many biological processes, including intracel… WebFeb 11, 2024 · Here, we focus on peptidyl prolyl cis/trans isomerases (PPIases) to dissect prolyl isomerization from other dynamic events. We reveal the contribution of PPIase on … WebEnter the email address you signed up with and we'll email you a reset link. sivery.github.io