Cy-fbp/sbpase
WebMay 25, 2016 · In Pp SBPase, a β-hairpin is formed in the α2–α4 loop containing Cys120 and Cys125 instead of helix α3 in Pp FBPase. In Pp FBPase, the β4–β5 loop containing Cys224 and Cys241 is extended with respect to the corresponding loop in Pp SBPase by 22 amino acids (34 vs. 12 residues). WebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7-176.9 μM) against cy-FBP/SBPase.
Cy-fbp/sbpase
Did you know?
WebWe describe the crystal structure of cy‐FBP/SBPase +AMP+FBP, which is dynamic and harbors at least three regulatory domains. The state of cy‐FBP/SBPase is changed among three potential states in the presence of different regulators: initial non‐active dimer state, non‐active tetramer state and active tetramer state. In the non‐active dimer state, a … Web(2014) Feng et al. FEBS Journal. Cyanobacterial fructose-1,6/sedoheptulose-1,7-bisphosphatase (cy-FBP/SBPase) plays a vital role in gluconeogenesis and in the ...
Web16 Cyanobacteria fructose-1, 6-/sedoheptanose-1, 7-diphosphatase (Cy-FBP/SBPase) is 17 an essential regulatory enzyme in cyanobacterial photosynthesis and a potential target … WebJun 1, 2013 · In this study, as potential inhibitors of Cy-FBP/SBPase, a series of novel chromone-connecting benzohydrazone compounds (Novel N′-((4-oxo-4H-chromen-3 …
WebThe invention provides a chromone-containing benzimidazole bifurazan compound with a Cy-FBP/SBPase inhibition effect and a preparation method of the chromone-containing benzimidazole bifurazan compound. The molecular structure of the compound is shown as WebSep 2, 2016 · Sedoheptulose-1, 7-bisphosphatase (SBPase) is an important enzyme involved in photosynthetic carbon fixation in the Calvin cycle. Here, we report the impact of changes in SBPase activity on...
WebApr 1, 2012 · Fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) is a potential important target enzyme for finding inhibitors to solve harmful algal bloom. In this paper, …
WebJun 1, 2013 · As potential inhibitors of Cy-FBP/SBPase, a series of novel type chromone-benzohydrazone derivatives were designed and synthesized. Amongst these … how to sit with a knee immobilizerWebcy–FBP/SBPase exhibits unique biochemical charac-teristics compared with previously characterized FBPase enzymes. It has a wider substrate range and hydrolyzes both FBP … how to sit with better postureWebFeb 13, 2014 · Cyanobacterial fructose-1, 6-/sedoheptulose-1, 7-bisphoshatase (cy-FBP/SBPase) is a potential enzymatic target for screening novel inhibitors that can … nova instance wow tbcWebMar 1, 2006 · We have demonstrated that transgenic tobacco (TpFS) plants expressing cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) in chloroplasts exhibit increased photosynthetic CO 2 fixation capacity and final dry matter under atmospheric conditions (360 ppm CO 2) ( Miyagawa et al. 2001 ). how to sit with bad kneesWebTo change the setting of the CICS SIT table property, ask the CICS system programmer and the external security manager. The SIT property defines the intersystem refresh delay, … how to sit with blockbusterWebIn the present study, we targeted the substrate binding pocket of cy-FBP/SBPase. A series of novel hit compounds from the SPECs database were selected by using a pharmacophore-based virtual screening strategy. Most of the compounds tested exhibited moderate inhibitory activities (IC50 = 20.7−176.9 μM) against cy-FBP/SBPase. nova instructor websiteWebJan 27, 2024 · quantitative RT-PCR was used to detect the presence of the FBP/SBPase transcript in lines S B and S B C 6, cytochrome c 6 in lines C 6, S B C 6 and SC 6, and SBPase in lines S and SC 6 (Fig. 1a). We analysed total extractable FBPase activity in the leaves of the cv. Petite Havana T2/T3 & nova installations windows