WebAug 6, 2010 · A set of 123 primary breast tumors and matched normal tissue was analyzed by two-dimensional (2D) gel electrophoresis, and a novel protein, C7orf24, was identified as being upregulated in cancer... WebThe hypothetical protein C7orf24 has been implicated as a cancer marker with a potential role in cell proliferation (1–3). We have identified C7orf24 as -glutamyl cyclotransferase …
Entry - *137170 - GAMMA-GLUTAMYL CYCLOTRANSFERASE; GGCT …
WebGamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is encoded by the gene C7orf24, and the enzyme participates in the gamma-glutamyl cycle. WebMay 1, 2008 · The next highest match is the human protein C7orf24, whose crystal structure was recently solved by the CESG 17. This protein of unknown function displays 23.2% sequence identify with At3g28950 and alignment over 99 C α 18. Several cancer cell lines also express C7orf24, and siRNA knock-down of protein levels produced an … resistant starch nhs
A novel tumor-related protein, C7orf24, identified by …
WebAug 8, 2008 · The hypothetical protein C7orf24 has been implicated as a cancer marker with a potential role in cell proliferation. We have identified C7orf24 as γ-glutamyl … WebDue its ability to provide a global snapshot of kidney physiology, urine has emerged as a highly promising, non-invasive source in the search for new molecular indicators of disease diagnosis, prognosis, and surveillance. In particular, proteomics represents an ideal strategy for the identification of urinary protein markers; thus, a urinomic approach could also … WebSep 22, 2016 · Background Chromosome 7 open reading frame 24 (C7orf24) was originally identified as a highly expressed protein in various types of cancer, and later shown to be a γ-glutamylcyclotransferase (GGCT). GGCT depletion in cancer cells has anti-proliferative effects in vitro and in vivo, and it is therefore considered a promising candidate as a … protein trichome birefringence-like 39